Careers
Work For Us

We are excited to see you are interested in working for A4P.

As a diverse and engaging workplace, we are always looking for forward-thinking and motivated people to join our teams.

Why work for us? Our success to date is all due to our employees who we hope to inspire and develop while working in their chosen roles. We thrive to provide our employees with the best work-life balance through ensuring flexibility and help where needed.

Data Curation and Anonymization Specialist

Main Responsibilities

The individual contributor as a skilled Biomedical Data Curation and Anonymization Specialist (DCAS) will support research and development projects in digital pathology for our client. The DCAS will curate pathology image datasets and associated metadata so that they are well organized and  accurate, and will apply data anonymization tools to anonymize digital pathology images and associated image, clinical and genetic metadata. The DCAS will work with multiple stakeholders to locate, transfer, and prepare the data for use by pathologists and data scientists. This will include overseeing and coordinating data preparation & transfer operations from both internal and external data providers.

The responsibilities will be to:

The DCAS will be responsible for ensuring digital pathology (DP) images and multidimensional associated metadata ingested into the DP storage platform are well organized, anonymized and meet technical quality standards required for DP algorithm development. The role will not require visual assessment of image content, however, previous experience working with DP or other imaging modalities will help the successful candidate accomplish the listed tasks:

 

  • – Run data anonymization algorithms on digital pathology images, image metadata, clinical data, and genetic data
  • – Contribute to the maintenance and optimization of digital pathology image/data anonymization algorithms
  • – Use and improve metadata storage and management tools
  • – Manage digital pathology project data, curate image, clinical, and genetic metadata
  • – Support and coordinate data transfers and ingestion from internal and external parties, carry out technical quality control on ingested data
  • – Communicate with external data providers about data transfer requirements, share technical issues with vendors, oversee and contribute to their resolution
  • – Work closely with groups across the organization to locate and access data from diverse company internal systems
  • – Contribute to ongoing development of A4P products and services

This list is not exhaustive and other tasks in line with the role might be assigned

Profile

Education and Experience

  • A minimum of a Master’s degree in Computer Science, Data Science, or related field, or 2+ years working in a data curation or data management role.
  • Experience with general tools and techniques used in anonymization workflows:

Practical experience and fluency in R and Python

Practical experience working with APIs

  • Strong organizational skills with meticulous attention to detail
  • Demonstrated communication skills of technical information, both understanding and expressing requirements from stakeholders with a high level of bioinformatics expertise (i.e. an ability to both work with and communicate about large datasets containing imaging, clinical, demographic, genetic etc. data).
  • Experience in managing large datasets
  • Ability to work independently, follow up on verbal discussions with concrete action steps, and take initiative.
  • Business fluency in English (written and spoken)
  • Should have practical experience with cloud services (AWS, Azure, GCP)
  • Should have prior experience with digital pathology or imaging and clinical data
  • Should have familiarity with Data modeling
  • Should have familiarity with database software and organizational systems such as LIMS

Personal Attributes

Engaging, enthusiastic, self-motivated, confident, self-assured and a team player. Willing to interact with large organizations on behalf of a small company

  • Open to embrace new ideas and ability to operate in a flexible manner
  • Strong interpersonal skills and a consultative mindset, with the ability to influence without direct authority, and to develop strong partnerships
  • “Self-starter”; strong sense of responsibility with demonstrable comfort in an entrepreneurial environment.
  • Good problem-solving ability, breaking down complex problems into distinct parts, managing uncertainty, understanding, anticipating interdependencies.
  • Demonstrable ability to prioritize activities with strong attention to detail and effectively multi-task across deliverables
  • Gain client trust and confidence in A4P abilities to deliver clients objectives and requirements
  • Willingness and availability to travel and work at client’s site(s) for short periods of time.
  • Willingness and availability to travel and work at A4P’s location in Sandwich, Kent on regular (frequency negotiable) basis for duration of employment.
  • Demonstrable significant understanding of the research activities undertaken within a drug development organization
  • Ability to develop effective relationships with external service partners
  • Full driving licence may be advantageous though not essential

Hours of Work: This position is a full-time role based on 37.5 hrs. per week, excluding lunch & holidays with an initial 3-month probationary period.  A4P operates a degree of informal flexibility as regards working hours attendance.

Benefits: A4P offer staff membership of BUPA Healthcare and Dental Schemes on successful completion of the probationary period

Job Application - Data Curation and Anonymization Specialist

Name
Max. file size: 50 MB.
Consent
Clinical Biosample Operations Project Manager

Main Responsibilities

The successful candidate will be responsible for ensuring strategic operational input into clinical laboratory testing of human biological specimens and the efficient operational deployment of such clinical laboratory testing at the programme level (including biomarkers, central safety testing and clinical bioanlysis for pharmacokinetic assessment).  

The responsibilities will be to:

  • Provide appropriate operational contribution to the inclusion of laboratory testing of human biological specimens into clinical programmes and trials  
  • Planning, coordinating, and overseeing all operational activities required to manage the lifecycle of clinical biosamples (including companion diagnostic samples) – collection, processing, analysis, data delivery process and final sample disposition 
  • Ensure all the laboratory components within planning operational delivery documents are accurate and fit for purpose.  Ensuring strategy for the sampling plan is deployed and lessons learnt are communicated to the study level personnel to ensure optimal synergies of activities for study level activities in assigned projects 
  • Collaboration with Biomarker scientists as well as operational teams, diagnostic partners, external CRO & Central Labs, and biomarker vendors to execute the biosample operational strategies on one or multiple studies/projects 
  • Management of the development and oversight of the biosample analysis timelines, budget, risk and quality plans 
  • Oversee delivery of laboratory services and data from external providers at a project level. 
  • Provide rapid, regular and frequent updates of all activities to the clinical study teams. 
  • Contribute to ongoing development of A4P products and services 
  • This list is not exhaustive and other tasks in line with the role might be assigned 

 

Profile

Education and Experience  

  • Proven experience in clinical development and operational deployment of biological assays obtained in a major pharmaceutical company or large CRO organisation within a project management role is required. 
  • Proven experience in oversight of external partners, laboratory service providers is required. 
  • Biological laboratory experience and biomarker scientific background is desirable. 

Personal Attributes 

Engaging, enthusiastic, self-motivated, confident, self-assured and a team player. Willing to interact with large organizations on behalf of a small company  

  • Demonstrable ability to prioritize activities with strong attention to detail and effectively multi-task across deliverables 
  • Excellent communication skills in both written and oral areas. Strong presenting skills 
  • Gain client trust and confidence in A4P abilities to deliver clients objectives and requirements 
  • Willingness and availability to travel and work at client’s site(s) for short periods of time. 
  • Willingness and availability to travel and work at A4P’s location in Sandwich, Kent on regular (frequency negotiable) basis for duration of employment. 
  • Demonstrable significant understanding of the research activities undertaken within a drug development organization  
  • Ability to develop effective relationships with external service partners 
  • Full driving licence may be advantageous though not essential 

Hours of Work: This position is a full-time role based on 37.5 hrs. per week, excluding lunch & holidays with an initial 3-month probationary period.  A4P operates a degree of informal flexibility as regards working hours attendance.   

Benefits: A4P offer staff membership of BUPA Healthcare and Dental Schemes on successful completion of the probationary period 

Job Application - Clinical Biosample Operations Project Manager

Name
Max. file size: 50 MB.
Consent
Biomarker Operations Manager

Main Responsibilities

Working within a Translational Medicine department of one of our clients, we are looking for a highly motivated individual to coordinate the preparation, implementation, and follow-up of biological analyses (ie PK, PD and biomarkers) in clinical trials in close interaction with Translational Medicine scientists, Clinical Study managers, Clinical Leads, Medical Directors and CROs. The successful candidate will be autonomous, proactive and collaborative with experience working in a clinical development environment.

The responsibilities will be to:

  • Contribute to the preparation of biological analyses in clinical trials by
    • participating to the selection of analytical laboratories (including service providers and/or commercial partners),
    • managing contracts with the support of a legal advisor,
    • planning and following-up the activities related to the implementation of biological analyses in clinical trials (e.g. assay transfer, kit preparation, sample collection procedures, shipping requirements, CRF review, analytical data collection/reporting and data transfer) with different service providers.
  • Follow-up and monitor the activities related to biological analyses during ongoing clinical trials (including coordination with the central lab and the other laboratories, follow-up of samples), identify study or project issues and solve them. Contribute to the preparation of the budget related to these activities as well as its follow-up.
  • Collaborate on the transfer, review and analysis of the corresponding results and ensure appropriate data review and accurate data reporting.
  • Support the development of dedicated sections of interim analysis and study report.

 

Profile

  • You hold a Bachelor or Master degree in Life Sciences or PharmD.
  • Ideally, you have a minimum of 3-year experience in organizing, implementing and monitoring analysis of biological markers during clinical trials, but candidates with less biomarker specific experience who have extensive experience in clinical operations will also be considered.
  • Experience in oncology/immuno-oncology is an advantage.
  • Prior experience in a laboratory environment is important to be able to coordinate experiments in clinical settings.
  • Experience in the follow-up of contractual aspects and relations is an advantage.
  • You have strong problem-solving skills
  • You are open-minded and have excellent interpersonal and communication skills.
  • You have a good understanding of GCP/GCLP guidelines and current global regulations.
  • You are fluent in English (oral and written), French language would be useful.
  • Well organized and resilient, you are able to adapt to changes in priorities and to work effectively on multiple programs in a fast-paced environment.
  • Although largely autonomous, you are collaborative and are happy to work with internal and external stakeholders.
  • You master Standard Office tools (knowledge in MS project is an asset.
  • Since the job scope/role could evolve as the company grows, you can adapt to changing needs.

Job Application - BIomarker Operations Manager

Name
Max. file size: 50 MB.
Consent